Plasmid DNA is a critical starting material for cell and gene therapies, viral vectors, mRNA therapeutics, and DNA vaccines, but manufacturing it consistently at the required quality and scale can present significant technical and operational challenges.

This webinar will examine key considerations for optimizing plasmid design, process development, production, and analytical control across development stages. Attendees will learn how advanced plasmid engineering, high-performance production strains, scalable purification technologies, and phase-appropriate quality strategies can help improve yield, supercoiling, ITR integrity, and manufacturing timelines.

The session will also explore how an integrated approach spanning plasmid design, CMC development, analytics, and GMP manufacturing can reduce risk and support programs from preclinical development through commercialization.